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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK4
All Species:
28.18
Human Site:
Y183
Identified Species:
56.36
UniProt:
P51957
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51957
NP_003148.2
841
94597
Y183
E
L
F
S
N
K
P
Y
N
Y
K
S
D
V
W
Chimpanzee
Pan troglodytes
XP_516519
889
99702
Y277
E
L
F
S
N
K
P
Y
N
Y
K
S
D
V
W
Rhesus Macaque
Macaca mulatta
XP_001082793
1258
142958
Y180
E
I
C
E
N
K
P
Y
N
N
K
S
D
I
W
Dog
Lupus familis
XP_533795
879
98359
F206
E
S
Q
V
V
E
W
F
V
Q
I
A
M
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1J2
792
88976
Y183
E
L
F
S
N
K
P
Y
N
Y
K
S
D
V
W
Rat
Rattus norvegicus
NP_001013152
793
89178
Y183
E
L
F
S
N
K
P
Y
N
Y
K
S
D
V
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521008
756
85471
S153
L
F
S
N
R
P
Y
S
Y
K
S
D
V
W
A
Chicken
Gallus gallus
XP_414252
807
90823
Y183
E
L
F
S
N
K
P
Y
N
Y
K
S
D
V
W
Frog
Xenopus laevis
Q7ZZC8
944
104521
Y210
E
I
C
Q
G
V
K
Y
S
F
K
S
D
I
W
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
K94
T
L
A
D
Y
I
Q
K
R
C
N
S
L
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SLI2
612
68818
Q9
E
Q
Y
E
F
L
E
Q
I
G
K
G
S
F
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48479
858
94329
Y212
E
I
C
A
A
E
K
Y
T
L
K
S
D
I
W
Conservation
Percent
Protein Identity:
100
88.4
25.5
73
N.A.
72.2
72.4
N.A.
57
58.8
21
25.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
88.6
42.5
80.1
N.A.
80.5
79.7
N.A.
68
71.6
37.7
43.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
66.6
6.6
N.A.
100
100
N.A.
0
100
40
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
80
26.6
N.A.
100
100
N.A.
6.6
100
66.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.6
N.A.
20.9
Protein Similarity:
N.A.
N.A.
N.A.
44.3
N.A.
39.2
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
40
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
9
0
0
0
0
0
0
9
0
9
9
% A
% Cys:
0
0
25
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
0
9
67
0
9
% D
% Glu:
84
0
0
17
0
17
9
0
0
0
0
0
0
0
0
% E
% Phe:
0
9
42
0
9
0
0
9
0
9
0
0
0
9
0
% F
% Gly:
0
0
0
0
9
0
0
0
0
9
0
9
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
25
0
0
0
9
0
0
9
0
9
0
0
25
0
% I
% Lys:
0
0
0
0
0
50
17
9
0
9
75
0
0
0
0
% K
% Leu:
9
50
0
0
0
9
0
0
0
9
0
0
9
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
9
50
0
0
0
50
9
9
0
0
0
0
% N
% Pro:
0
0
0
0
0
9
50
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
9
9
0
0
9
9
0
9
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% R
% Ser:
0
9
9
42
0
0
0
9
9
0
9
75
9
0
0
% S
% Thr:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% T
% Val:
0
0
0
9
9
9
0
0
9
0
0
0
9
42
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
67
% W
% Tyr:
0
0
9
0
9
0
9
67
9
42
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _